Mitochondria-induced inflammation: The dark side of a cell’s “powerhouse”
The word “immunity” conjures up an image of our body fighting against infections. We picture our immune cells heroically battling against foreign, unwanted substances – viruses and bacteria – that...
Uncovering the secrets of mitochondria: The road to an anti-aging remedy
One of the holy grails of medicine is a cure for aging, and it has been the inspiration of many myths and legends, such as the Elixir of Life, the...
Trained Immunity? What’s that?!
The innate and adaptive immune systems Our immune system is broadly divided into two separate “arms” that communicate with each other to protect us from infections. These two factions are...
The mitochondria – the powerhouse against infectious diseases
Mitochondria are not just the powerhouse of the cell. Known for their role in energy production and metabolism, they also play a significantly in the immune system1. While oxidative phosphorylation...
Advancements in mitochondrial DNA editing: A gateway to curing incurable diseases
Mitochondria, often referred to as our cells' powerhouses, contain their own unique DNA known as mitochondrial DNA (mtDNA). Mutations in mtDNA can trigger severe disorders like Mitochondrial Myopathy (marked by...
How does exercise help our mitochondria?
The current world marathon record is set by Eilud Kipchoge, a Kenyan marathoner who finished a full 42.195km in only 2:01:09 in the 2022 Berlin Marathon. I, on the other...
Redox medicine – the double-edged sword of oxidants
You may have read the packaging on an item at the grocery store and seen the words “High in Antioxidants” shining out. Antioxidants must be important then – why else...
Who is mitochondrial Eve – the mother of all humans?
The blueprint of our body lies within our DNA – the genetic material we inherit from our parents. It is common knowledge that equal parts of this DNA come from...
Mitochondria: bounded by membrane, but of unbounded impact
Undoubtedly, Power, Sex, Suicide is a book with a very punchy and eye-catching title. The title summarizes the critical message the author Nick Lane wants to convey: mitochondria are way...
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